Identification of E-protein complexes controlling natural killer cell fate and tumour immunity [ 2017 - 2019 ]

Research Grant

Researchers: A/Pr Nicholas Huntington (Principal investigator) ,  A/Pr Sandra Nicholson ,  Prof Eric Vivier ,  Prof Lynn Corcoran

Brief description Diverse immune cell types are essential for effective broad-spectrum immunity. Master regulators control this diversity and have a well-characterized role in the development of antigen-specific immunity. In contrast, we lack mechanistic understanding of how master regulators control antigen-unspecific, innate immunity. Understanding the mechanism behind this will explain how diverse white blood cells can develop and reveal strategies to skew their development to improve immunity in humans.

Funding Amount $AUD 699,714.36

Funding Scheme Project Grants

Notes Standard Project Grant