Identification and development of proteins which interact with the innate immune system as malaria vaccine candidates [ 2013 - ]

Research Grant

Researchers: Dr Greta Weiss (Principal investigator)

Brief description Parasites causing malaria live inside red blood cells. Some human proteins act in a chain reaction to destroy infected cells. Although these proteins recognise parasite-infected cells and the chain reaction starts, the infected cells are not destroyed due to parasite proteins which inhibit the human proteins. A vaccine could induce antibodies which block the parasite proteins inhibiting the human proteins so the immune system can function normally and kill infected cells, thus stopping malaria.

Funding Amount $299,564.00

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF