Host-pathogen interactions in clostridial myonecrosis [ 2015 - ]

Research Grant

Researchers: Prof Julian Rood (Principal investigator) ,  Prof Paul Hertzog

Brief description This project will show how the bacteria that cause gas gangrene interact with host cells in an infection. We will examine the expression of genes from both the host and the pathogen in a mouse disease model. The aims are to determine the impact of bacterial genes that are differentially regulated in an infected lesion, how gene expression of both the host and pathogen is modulated throughout the course of an infection and the role of host pathways in controlling the infection process.

Funding Amount $862,693.00

Funding Scheme Project Grants

Notes Standard Project Grant