Hormone-dependent autophagy and growth signalling in developmental cell death [ 2017 - ]

Research Grant

Researchers: Prof Sharad Kumar (Principal investigator) ,  Dr Donna Denton ,  Prof Eric Baehrecke

Brief description Cell death is essential for cell and tissue homeostasis and its dysregulation is associated with many diseases. We discovered a new mode of cell death that involves autophagy. We have now identified that TGF-β signalling pathway, which has roles in numerous human pathologies, is involved in autophagy-dependent cell death. Our proposed studies will further characterise this important signalling axis and study its significance in development, normal physiology and disease.

Funding Amount $613,447.00

Funding Scheme Project Grants

Notes Standard Project Grant