Hormonal responsive coding and non-coding genes in penile differentiation and hypospadias [ 2018 - 2020 ]

Research Grant

Researchers: Prof Marilyn Renfree (Principal investigator) ,  A/Pr Andrew Pask ,  E/Pr Geoffrey Shaw ,  E/Pr Jean Wilson

Brief description Hypospadias, a failure of the correct formation of the penis, is the second-most common birth defect, occurring in around 1% of boys. It causes distress to both newborn and parents, requiring surgical intervention, and is a burden of cost and is a risk to the child. Furthermore, it is frequently associated with other abnormalities. We have a novel model in which we can induce penis abnormalities and define the link between hormonal exposures and defective penis differentiation.

Funding Amount $AUD 846,874.95

Funding Scheme Project Grants

Notes Standard Project Grant