grant

HIV assembly, transport, egress and transfer from infected dendritic cells [ 2009 - 2013 ]

Also known as: HIV replication and exit within infected dendritic cells

Funded by National Health and Medical Research Council
Managed by The University of New South Wales
Managed by University of New South Wales
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/570917]

Researchers: A/Pr Stuart Turville (Principal investigator)

Brief description HIV-AIDS is the fourth leading killing disease worldwide, with the disease burden shifting towards women. Study of the HIV life cycle in cells known to be targetted during HIV transmission is key towards designing additional preventative measures in the form of topical gels known as microbicides. Mapping of the basic pathways of viral transport within such cells, will aid further drug discovery and-or appropriateness of use of existing drugs in microbicide formulations.

Funding Amount $AUD 511,629.56

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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Subjects
AIDS | Anterograde cytoskeletal transport of HIV particles | Anti-retroviral microbicides | Anti-retroviral pre-post exposure chemoprophylaxis | Applied Immunology (Incl. Antibody Engineering, Xenotransplantation and T-Cell Therapies) | Biomedical and Clinical Sciences | Dendritic cell and CD4 lymphocyte conjugation | HIV assembly and budding | HIV infection and release from dendritic cells | HIV transmission | Immunology | Virological synapse |
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