grant

Histone Deacetylase Inhibitors (HDIs) with antineoplastic and antiosteolytic properties [ 2008 - 2011 ]

Also known as: Histone Deacetylase Inhibitors in Bone Cancer Therapy

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/519239]

Researchers: Prof Andreas Evdokiou (Principal investigator) ,  A/Pr Lisa Butler Prof David Findlay

Brief description Metastatic bone disease is very common in patients with many forms of solid tumours. Our approach to use Histone Deacetylase Inhibitors (HDIs), to target bone metastases offers an exciting therapeutic potential. Treatment with HDIs will have the potential to suppress cancer-induced bone destruction by integrating the cytotoxic and osteotropic properties that reside within the same compound. Our preclinical data will facilitate the translation of HDIs to clinical trials for bone cancer.

Funding Amount $AUD 535,333.35

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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