Why is the hijacking of a human erythrocyte signalling pathway essential for malaria infection? [ 2015 - 2018 ]

Research Grant

Researchers: Prof Christian Doerig (Principal investigator) ,  Prof Andrew Tobin

Brief description Malaria drug resistance is spreading and the world needs cost-effective new drugs. We found 2 human enzymes, known targets of cancer chemotherapy, to be key for parasite survival in red blood cells. We aim to understand why these human proteins are crucial for the parasite and to identify new human proteins hijacked by malaria. This will open exciting options for antimalarial drug discovery: to harness funds invested in cancer drugs by targeting proteins with dual roles in cancer and malaria.

Funding Amount $AUD 510,890.46

Funding Scheme Project Grants

Notes Standard Project Grant