grant

Hearing protection conferred by P2X2 receptor signaling in the cochlea [ 2010 - 2013 ]

Also known as: Protection of hearing by ATP-gated ion channels

Funded by National Health and Medical Research Council
Managed by University of New South Wales
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/630618]

Researchers: Prof Gary Housley (Principal investigator) ,  Prof Allen Ryan

Brief description Hearing loss from noise damage and ageing is the principal sensory disability in our society. This project will determine the contribution of the P2X2 receptor to protection from noise-induced hearing loss. We have found that P2X2 knockout mice have minimal temporary threshold shift. We will investigate the physiological basis for this and determine why this mouse model has greater hearing loss with intense sound and faster age-related hearing loss compared with wildtype controls.

Funding Amount $AUD 580,019.09

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Medical and Health Sciences | Neurosciences | Noise-induced hearing loss | Sensory Systems | age-related hearing loss | auditory neuroscience | cochlea | deafness | effect of noise stress on hearing | hearing physiology | presbycusis | purinergic signaling | sensory disability |
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