HDL Elevation and Glucose Metabolism: A Mechanistic Proof-of-Concept Intervention Trial in Pre-Diabetes [ 2014 - 2017 ]

Research Grant

Researchers: Prof Bronwyn Kingwell (Principal investigator) ,  Dr Andrew Siebel ,  Prof Stephen Duffy

Brief description This clinical trial will investigate a new treatment strategy for type 2 diabetes. Building on our novel discovery that HDL (good cholesterol) lowers blood glucose, we will test whether HDL elevation over a month with a new drug (RVX-208) can improve glucose control in patients with pre-diabetes. If positive, these studies will support new therapeutic approaches to raise levels of circulating HDL for indications beyond vascular disease to manage type 2 diabetes.

Funding Amount $AUD 507,974.66

Funding Scheme Project Grants

Notes Standard Project Grant