Data

Harnessing the power of the innate immune system to protect livestock against disease

University of New England, Australia
Alexander, Annika ; Doyle, Emma ; CSIRO
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.25952/2by7-vv53&rft.title=Harnessing the power of the innate immune system to protect livestock against disease&rft.identifier=10.25952/2by7-vv53&rft.publisher=University of New England, Australia&rft.description=This collection of data is from four experimental trials between 2019 and 2022, investigating the effect of the immune stimulant Amplimune® (NovaVive Inc., Napanee, Ontario, Canada) on immune and physiological responses in Australian beef cattle. The aim was to explore the potential of the immune stimulant to enhance immune responses and protect cattle against a range of pathogens. At CSIRO’s Chiswick Research Station near Armidale, NSW, immune and physiological responses were measured following administration of Amplimune to cattle in vivo (live animal), or cattle immune cells in vitro (in the laboratory). Immune responses were measured using a haematological analyser, enzyme-linked immunosorbent assays, cell culture and RNA extraction, PCR and sequencing. Physiological responses were measured using temperature loggers, weight scales and physical assessment (by a veterinarian). These data (except the sequencing data) were all stored in excel spreadsheets. The sequencing data was stored as zipped fastq files.&rft.creator=Alexander, Annika &rft.creator=Doyle, Emma &rft.creator=CSIRO &rft.date=2023&rft.coverage=-30.604275146463166, 151.54406414690854&rft.coverage=Armidale, NSW, Australia&rft_rights=Rights holder: CSIRO&rft_rights=Rights holder: CSIRO&rft_rights=Access to this collection's metadata and/or files (if any) are restricted until 15 Jun 2024. Although the associated metadata is public, the files (if any) have not been approved for general release. Please phone or email the contact person for this collection to discuss access to the files.&rft_subject=Cattle&rft_subject=Immune stimulants&rft_subject=Innate immunity&rft_subject=Trained immunity&rft_subject=Amplimune&rft_subject=feedlot&rft_subject=Veterinary Immunology&rft_subject=AGRICULTURAL AND VETERINARY SCIENCES&rft_subject=VETERINARY SCIENCES&rft.type=dataset&rft.language=English Access the data

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Rights holder: CSIRO

Rights holder: CSIRO

Access to this collection's metadata and/or files (if any) are restricted until 15 Jun 2024. Although the associated metadata is public, the files (if any) have not been approved for general release. Please phone or email the contact person for this collection to discuss access to the files.

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This collection of data is from four experimental trials between 2019 and 2022, investigating the effect of the immune stimulant Amplimune® (NovaVive Inc., Napanee, Ontario, Canada) on immune and physiological responses in Australian beef cattle. The aim was to explore the potential of the immune stimulant to enhance immune responses and protect cattle against a range of pathogens. At CSIRO’s Chiswick Research Station near Armidale, NSW, immune and physiological responses were measured following administration of Amplimune to cattle in vivo (live animal), or cattle immune cells in vitro (in the laboratory). Immune responses were measured using a haematological analyser, enzyme-linked immunosorbent assays, cell culture and RNA extraction, PCR and sequencing. Physiological responses were measured using temperature loggers, weight scales and physical assessment (by a veterinarian). These data (except the sequencing data) were all stored in excel spreadsheets. The sequencing data was stored as zipped fastq files.

Issued: 2023-06-16

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Spatial Coverage And Location

text: Armidale, NSW, Australia

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