Data

H proton MR Spectroscopy in Schizophrenia Study, Melbourne Neuropsychiatry Centre

The University of Melbourne
Professor Christos Pantelis (Owned by)
Viewed: [[ro.stat.viewed]] Cited: [[ro.stat.cited]] Accessed: [[ro.stat.accessed]]
ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft.title=H proton MR Spectroscopy in Schizophrenia Study, Melbourne Neuropsychiatry Centre&rft.publisher=The University of Melbourne&rft.description=Data from our own cross-sectional MRI work has identified bilaterally smaller hippocampal volumes in first-episode and chronic schizophrenia, while high-risk mindividuals did not eiffer from normal controls. This finding calls into question the neurodevelopmental hypothesis of schizophrenia.'H Proton MRS provides measures of neuronal integrity and density (NAA) while choline represents a major component of the myelin in the brain. Using MRS this study will examine the neural and non-neuronal elements of the hippocampus to assess the relative contribution of these elements to changes in hippocampal volume. This study will examine 30 patients from three groups (high-risk, first-episode, chronic schizophrenia) and matched healthy controls. The high-risk group and 15 controls will be re-assessed after the onset of psychosis. Patients will be recruited from EPPIC and PACE clinics at Orygen Youth Health. Controls will be recruited via an database established from previous research.&rft.creator=Professor Christos Pantelis&rft.date=2013&rft_subject=NEUROSCIENCES&rft_subject=MEDICAL AND HEALTH SCIENCES&rft.type=dataset&rft.language=English Access the data

Please use the contact information below to request access to this data.

Contact Information



Cite Saved to MyRDA Save to MyRDA

Access:

Other view details

The owner of this data collection may provide access to this data collection by negotiation. You could be required to indicate your intended use of the data, to meet any costs associated with providing you with the data, and to fulfill other terms and conditions as determined by the data owner / manager. Use of the data may also be subject to legal, ethical and commercial restrictions, requiring further permission from other individuals or groups, including ethics committees, project steering groups, and research participants.

Full description

Data from our own cross-sectional MRI work has identified bilaterally smaller hippocampal volumes in first-episode and chronic schizophrenia, while "high-risk" mindividuals did not eiffer from normal controls. This finding calls into question the neurodevelopmental hypothesis of schizophrenia.'H Proton MRS provides measures of neuronal integrity and density (NAA) while choline represents a major component of the myelin in the brain. Using MRS this study will examine the neural and non-neuronal elements of the hippocampus to assess the relative contribution of these elements to changes in hippocampal volume. This study will examine 30 patients from three groups ("high-risk, first-episode, chronic schizophrenia) and matched healthy controls. The high-risk group and 15 controls will be re-assessed after the onset of psychosis. Patients will be recruited from EPPIC and PACE clinics at Orygen Youth Health. Controls will be recruited via an database established from previous research.

This dataset is part of a larger collection

Click to explore relationships graph
Help

Related People

Subjects
Medical and Health Sciences | Neurosciences |

User Contributed Tags    

Login to tag this record with meaningful keywords to make it easier to discover

Similar data you may be interested in: