GPR88 as a novel target for fronto-striatal dysfunction in schizophrenia [ 2016 - ]

Research Grant

Researchers: Dr Chris Langmead (Principal investigator) ,  Dr Jess Nithianantharajah

Brief description GPR88 is a protein that is specifically found in the striatum, one of the main brain regions involved in schizophrenia. Studies in mice have showed that GPR88 may have a role in learning and memory; our early studies show that GPR88 controls the activity of a population of cells in the striatum. This project will determine the mechanism by which GPR88 controls the function of the striatum and how this translates into regulating brain circuitry and learning and memory relevant to schizophrenia.

Funding Amount $606,966.00

Funding Scheme Project Grants

Notes Standard Project Grant