Glutathione transferase Omega 1 as a novel target for sepsis and other inflammatory disorders. [ 2017 - 2020 ]

Research Grant

[Cite as]

Researchers: Prof Philip Board (Principal investigator) ,  A/Pr Aaron Oakley A/Pr Marco Casarotto

Brief description Sepsis is a major clinical problem that causes more deaths in Australia than breast, prostate or colon cancer. The deaths result from an overwhelming systemic inflammatory response to infection. We have discovered that this response is dependent on an enzyme called GSTO1-1 and that inhibitors can block the inflammatory response . In this study we will identify new drug like compounds that can inhibit GSTO1-1 and prevent death from sepsis.

Funding Amount $AUD 711,607.45

Funding Scheme Project Grants

Notes Standard Project Grant

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