grant

Glutathione transferase-derived compounds as therapeutic agents [ 2008 - 2011 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/471462]

Researchers: Prof Philip Board (Principal investigator) ,  A/Pr Marco Casarotto E/Pr Angela Dulhunty The Australian National University (Managed by)

Brief description Inhibition of cardiac calcium ion channels may be an effective new way of improving heart performance in patients with heart failure. This project will investigate how a glutathione transferase enzyme inhibits calcium ion channels in the heart and if small fragments of a muscle specific glutathione transferase can be used to specifically modify cardiac ryanodine receptor function. These fragments will provide the basis for the development of a new therapeutic approach.

Funding Amount $AUD 418,516.81

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857