Genomics of antiepileptic drug-induced Stevens Johnson syndrome [ 2016 - 2018 ]

Research Grant

Researchers: Prof Patrick Kwan (Principal investigator) ,  Dr Slavé Petrovski ,  Prof Pak Sham

Brief description Epilepsy affects 3% of people. Severe skin reactions to anti-epileptic drugs are unpredictable and potentially fatal. This project aims to better understand the complex genetic architecture of these reactions using the latest sequencing platforms applied to a unique collection of samples, followed by functional analysis. The findings will enhance the practice of precision medicine in epilepsy treatment, shed light on the mechanisms of these reactions, and inform better drug design in the future.

Funding Amount $AUD 512,456.75

Funding Scheme Project Grants

Notes Standard Project Grant