[Cite as http://purl.org/au-research/grants/nhmrc/389875]
Prof Nicholas Martin
Dr David Duffy
Prof Grant Montgomery
Brief description A large mole (melanocytic nevi) count is the strongest known risk factor for melanoma. An understanding of the factors governing naevus development may therefore lead to important insights into the etiology of melanoma. We shall carry out molecular genetic analysis of DNA samples collected from twins and their parents with the aim of identifying major genes affecting moliness, pigmentation and other risk factors for melanoma. The importance of this study is that it will significantly advance our understanding of the relationship between moliness and melanoma risk and may lead to new preventative and therapeutic interventions.
Funding Amount $AUD 642,116.09
Funding Scheme NHMRC Project Grants
Standard Project Grant