Genetic and genomic dissection of Polycomb repressive complex 2 (PRC2) in cancer [ 2011 - 2013 ]

Research Grant

Researchers: Prof Warren Alexander (Principal investigator) ,  A/Pr Marnie Blewitt ,  Dr Ian Majewski

Brief description The evolution of normal cells to cancer involves mutations that activate cancer-causing genes and/or prevent the actions of anti-cancer genes. It has become increasingly evident that cancer development also involves changes to epigenetic regulation, or control of gene activity by chemical modification of the gene or its environment rather that changes in DNA sequence. This project aims to explore the tumour suppressor activity of an important epigenetic regulatory complex in lymphoma.

Funding Amount $AUD 576,598.93

Funding Scheme Project Grants

Notes Standard Project Grant