Generation of protective immunity against severe influenza disease in Indigenous Australians [ 2017 - ]

Research Grant

Researchers: Prof Katherine Kedzierska (Principal investigator) ,  A/Pr Stephanie Gras ,  A/Pr Steven Tong ,  Prof Adrian Miller ,  Prof Anthony Purcell

Brief description Hospitalisation and death rates from influenza are high in the Indigenous population, especially when a new virus emerges. There is an urgent need for a vaccine that protects against all influenza strains. T cells recognising conserved viral regions elicit such protection. As T cells are restricted by proteins called HLAs, which vary across ethnicities, we will define T cell regions for HLAs prominent in Indigenous Australians and define how to generate protective immunity against influenza.

Funding Amount $1,630,970.00

Funding Scheme Project Grants

Notes Standard Project Grant