Next Generation Antibody Therapeutics [ 2019 - ]

Research Grant

Researchers: A/Pr Daniel Christ (Principal investigator)

Brief description This research will focus on an important problem, namely the limitations on specificity and persistence of human antibodies. Although often perceived as a perfect 'lock-and-key' phenomenon, many antibodies in fact display limited specificity and interact with unrelated targets resulting in short persistence and off-target effects. By deciphering mutational and structural mechanisms unpinning antibody specificity, my research will advance the development of next generation antibody therapeutics.

Funding Amount $717,275.00

Funding Scheme Research Fellowships

Notes Research Fellowship