grant

Gene Therapy for Neurofibromatosis types 1 and 2

Also known as: Ideas Grants

Funded by National Health and Medical Research Council
Managed by University of Sydney
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/2027987]

Funding Amount $1,450,562.00

Full description Neurofibromatoses (NF) are genetic cancer disorders that can have a lifelong impact on affected individuals. Current medical treatments are reactive, but gene therapy offers the promise of early intervention to reduce or negate tumour burden. We are using CRISPR-based techniques to correct pathogenic mutations. This has the potential to transform the treatment of NF1 and NF2 with a “cancer vaccine”, but the findings may have broad applicability for other genetic conditions.

Chief Investigator Assoc Prof Aaron Schindeler

Date Announced 2023-12-15T00:00:00

Sector University

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Spatial Coverage And Location

text: NSW

Subjects
Basic Science Research | Gene and Molecular Therapy | Medical Biotechnology | Technology | adeno-associated virus | biomedical and clinical sciences | cell culture | familial cancer | gene targeting | knockout mouse |
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