grant

Gene therapy to improve corneal graft survival [ 2009 - 2012 ]

Also known as: Gene therapy of the cornea

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/535000]

Researchers: E/Pr Keryn Williams (Principal investigator) ,  A/Pr Sonja Klebe Dr Helen Brereton E/Pr Douglas Coster

Brief description The goal of our work is to improve outcomes for patients who are blind or seriously visually impaired as a result of corneal disease. Such patients can regain vision through a corneal transplant, but many such transplants fail. A corneal graft may fail because of an unwanted immune response, because blood vessels grow into the graft, or because some corneal cells die. We plan to transfer genes to the donor cornea in the laboratory, prior to corneal transplantation, to avoid such failure.

Funding Amount $AUD 514,048.89

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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