Gene Identification for Inherited Peripheral Neuropathies by applying Next Generation Sequencing [ 2013 - 2015 ]

Research Grant

Researchers: A/Pr Marina Kennerson (Principal investigator) ,  Prof Garth Nicholson

Brief description Our goal is to study the biology underlying the death of motor and sensory nerves by identifying novel genes causing Charcot-Marie-Tooth (CMT) neuropathy. Using massively parallel sequencing we will systematically analyse the novel DNA changes througout the genome in CMT families in which the underlying gene mutation is unknown. Discovery of genes causing inherited peripheral neuropathies will elucidate mechanisms causing neurodegeneration and lead to targeted therapeutic treatment strategies to prevent the death of motor and sensory nerves.

Funding Amount $AUD 605,058.01

Funding Scheme Project Grants

Notes Standard Project Grant