Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1045465]
Researchers:
A/Pr Tony Roscioli
(Principal investigator)
,
A/Pr Jo Huiqing Zhou
,
Dr Michael Buckley
,
Prof Edwin Kirk
,
Prof Hans Van Bokhoven
View all 6 related researchers
Brief description Cleft lip/palate (CL/P) is among the most common malformation disorders but the causes of this condition are largely unknown. We do know that gene mutations cause CL/P in some people. We have also shown that the p63 gene may influence the activity level of genes involved in CL/P by attaching to regulatory elements near these genes. Changes in as yet unidentified genes controlled by p63 are strong possibilities for the cause of CL/P. We will test these by next generation sequencing, a technique that analyses all human genes.
Funding Amount $AUD 583,617.35
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1045465
- PURL : https://purl.org/au-research/grants/nhmrc/1045465