Gene editing to cure sickle cell disease [ 1/1/2021 - 12/31/2024 ]

Research Grant

Brief description Sickle Cell Disease was the first molecular disease described in man, and is the most prevalent. In some African countries, India and the Middle East, up to 20% of the population carry the sickle gene mutation. In developing countries, 90% of children die before 5 years of age. In developed countries, patients suffer a lifetime of chronic pain and die ~20 years early. We will employ new gene editing approaches to repair the mutation or recruit fetal hemoglobin to cure SCD in human samples.

Funding Amount $825,864

Funding Scheme Ideas Grants

Chief Investigator Prof Andrew Perkins

Notes Ideas Grants