Gamma-Delta Tregs, CD8 Tregs and selected natural Tregs to treat renal injury [ 2010 - 2013 ]

Research Grant

Researchers: Prof Stephen Alexander (Principal investigator) ,  Dr Yiping Wang ,  Dr Yuan Min Wang ,  Prof David Harris

Brief description Chronic kidney disease (CKD) progresses due to ongoing damage to the kidney. We have identified three types of white cells that can reduce kidney damage in CKD. The first is a unique set of gamma-delta T cells that expand in the kidney and protect against injury. The second is a restricted set of CD8 T cell that can protect against kidney injury. The third are targeted natural regulatory T cells. These studies develop each of these three subsets as potential cellular therapies in CKD.

Funding Amount $AUD 605,096.28

Funding Scheme Project Grants

Notes Standard Project Grant