Data

G-Quadruplex structural motifs modulate protein-RNA interactions within the transcriptome

The University of Western Australia
Bhatt, Uditi ; Smith, Nicole ; Mergny, Jean-Louis ; Cucchiarini, Anne ; Gros, Julien ; Evans, Cameron ; Iyer, K. S
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.5281/zenodo.17069363&rft.title=G-Quadruplex structural motifs modulate protein-RNA interactions within the transcriptome&rft.identifier=10.5281/zenodo.17069363&rft.publisher=Zenodo&rft.description=Additional data for G-Quadruplex structural motifs modulate protein-RNA interactions within the transcriptome.  raw_counts_filtered.csv: Raw counts for RIP-seq experiment. Genes with less than 10 counts across all samples removed. Dataset used for all further analysis of IP (FR) vs Input (Inp), K+ (K) vs Li+ (L), Volcano plots, MA plots, Heatmaps, Karyoplots, etc. Replicate 1 = P5, Replicate 2 = P6, Replicate 3 = P9. Additional_Source_Data.xlsx: Source data for RT-qPCR, Venn diagram, Gene Set Enrichment Analysis, Thermal Difference Spectra, Circular Dichroism, Thioflavin-T (ThT) and N-methyl mesoporphyrin IX (NMM) fluorescence. RNA_pg4s_20.csv: G4-iM Grinder results of predicted G-quadruplexes (pG4s) across the human transcriptome (Ensembl release 109). Filtered for pG4s with a mimumum score of 20. Dataset used for all pG4-associated analysis.&rft.creator=Bhatt, Uditi &rft.creator=Smith, Nicole &rft.creator=Mergny, Jean-Louis &rft.creator=Cucchiarini, Anne &rft.creator=Gros, Julien &rft.creator=Evans, Cameron &rft.creator=Iyer, K. S &rft.date=2025&rft.relation=http://research-repository.uwa.edu.au/en/publications/105e1410-ef02-47bc-b10f-a7f01b5bc4de&rft.type=dataset&rft.language=English Access the data
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Additional data for "G-Quadruplex structural motifs modulate protein-RNA interactions within the transcriptome".  raw_counts_filtered.csv: Raw counts for RIP-seq experiment. Genes with less than 10 counts across all samples removed. Dataset used for all further analysis of IP (FR) vs Input (Inp), K+ (K) vs Li+ (L), Volcano plots, MA plots, Heatmaps, Karyoplots, etc. Replicate 1 = P5, Replicate 2 = P6, Replicate 3 = P9. Additional_Source_Data.xlsx: Source data for RT-qPCR, Venn diagram, Gene Set Enrichment Analysis, Thermal Difference Spectra, Circular Dichroism, Thioflavin-T (ThT) and N-methyl mesoporphyrin IX (NMM) fluorescence. RNA_pg4s_20.csv: G4-iM Grinder results of predicted G-quadruplexes (pG4s) across the human transcriptome (Ensembl release 109). Filtered for pG4s with a mimumum score of 20. Dataset used for all pG4-associated analysis.

Notes

External Organisations
École polytechnique
Associated Persons
Jean-Louis Mergny (Supervisor); Anne Cucchiarini (Contributor); Julien Gros (Contributor)

Issued: 2025-09-06

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