Functional resolution of PTEX, the exporter of virulence factors in malaria parasites. [ 2017 - 2020 ]

Research Grant

Researchers: Prof Brendan Crabb (Principal investigator) ,  Dr Paul Gilson ,  Dr Travis Beddoe ,  Prof Tania De Koning-Ward

Brief description Almost half a million people die each year of malaria and nearly half the world’s population are at risk. To eliminate malaria this century we will need new drugs and vaccine to fight the disease. One potential drug target are the molecular gateways called PTEX, that are used by parasites to export virulence proteins into their human host cells. This grant aims to understand how the PTEX molecular machines work so we can develop new drugs to block them and kill the parasites.

Funding Amount $AUD 640,586.11

Funding Scheme Project Grants

Notes Standard Project Grant