Functional dyspepsia: Characterisation of the immunopathology and testing a novel therapeutic strategy. [ 2014 - 2018 ]

Research Grant

Researchers: Prof Nicholas Talley (Principal investigator) ,  Dr Natasha Koloski ,  Dr Nick Powell ,  Prof Gerald Holtmann ,  Prof Marjorie Walker
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Brief description Dyspepsia, unexplained stomach discomfort and pain, is a common and costly problem; few effective treatments exist and the causes are unknown. We have found that the numbers of a type of immune cell, the eosinophil, are increased in the top of the small bowel in patients with dyspepsia. This study will explore the mechanisms that lead to increased eosinophils and then test the effectiveness of a treatment to suppress this overactive immune response which could rapidly change clinical practice.

Funding Amount $AUD 739,604.05

Funding Scheme Project Grants

Notes Standard Project Grant