Functional dissection of the malaria RhopH complex and its contribution to new permeation pathways [ 2015 - ]

Research Grant

Researchers: Prof Tania de Koning-Ward (Principal investigator) ,  Dr Paul Gilson

Brief description The ability of Plasmodium to invade and remodel its host erythrocyte are the most significant contributors to its ability to cause the disease malaria. This project aims to understand how proteins secreted from a specialized rhoptry organelle during erythrocyte invasion help Plasmodium to remodel the erythrocyte so that the parasite can gain access to the vital nutrients it requires for survival. This research will validate whether drugs targeting the rhoptry proteins are viable drug targets.

Funding Amount $583,813.00

Funding Scheme Project Grants

Notes Standard Project Grant