grant

Functional contribution of fetal microchimeric cells in transgenic models of maternal tissue repair in and after pregnancy [ 2009 - 2012 ]

Also known as: How fetal cells that persist after pregnancy repair damaged tissues in women.

Funded by National Health and Medical Research Council
Managed by The University of Queensland
Managed by University of Queensland
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/569822]

Researchers: Prof Nicholas Fisk (Principal investigator) ,  A/Pr George Bou-Gharios ,  A/Pr Kiarash Khosrotehrani

Brief description Fetal stem cells cross into the mother during pregnancy and persist lifelong in her tissues. To determine whether helpful or harmful, we will study how these cells contribute to healing both after acute injury and in chronic genetic models like brittle-bone disease and muscular dystrophy. This research will inform long-term consequences of pregnancy, important for women's health and longevity, and help develop a promising form of stem cell therapy.

Funding Amount $AUD 542,462.24

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Biomedical and Clinical Sciences | Fetomaternal cell trafficking | Fetomaternal microchimerism | Nutrition and Dietetics | Osteogenesis imperfecta | Pregnancy complications | Public Health Nutrition | Stem cell therapy | Stem cells | Termination of pregnancy | Tissue regeneration | Women's health |
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