Functional characterization and therapeutic targeting of the novel long noncoding RNA MYCN-AS [ 2016 - 2018 ]

Research Grant

Researchers: A/Pr Tao Liu (Principal investigator) ,  A/Pr Marcel Dinger

Brief description Cancer is the most common cause of death from diseases in children. Neuroblastoma is the most common solid tumour in early childhood. In this application, we will establish the role of gene amplification of a novel long non-protein-coding RNA in blocking tumour suppressor gene expression and promoting neuroblastoma progression. We will also establish the anti-cancer efficacy of a novel therapy targeting the long non-protein-coding RNA.

Funding Amount $AUD 665,335.71

Funding Scheme Project Grants

Notes Standard Project Grant