Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/428206]Researchers: Dr Nathaniel Brown (Principal investigator) , Mark Wickham
Brief description Salmonella and E. coli cause enteritis and diarrhoea in a large proportion of the world's population including Australia. Certain strains of Salmonella also cause a more serious disease called typhoid fever. Together, diseases caused by Salmonella and E. coli are a major cause of illness and death. In order to cause disease Salmonella and E. coli use a specialised apparatus that functions like a needle and syringe to inject Salmonella proteins into human cells. These proteins that are injected into human cells actively reprogram human cells to benefit the disease causing bacteria. We have recently discovered a new family of injected proteins and we aim to determine how these new proteins reprogram human cells and what this contributes to diarrhoea and typhoid fever. This information may lead to the development of more effective treatments for these important diseases.
Funding Amount $AUD 510,183.42
Funding Scheme NHMRC Project Grants
Notes New Investigator Grant
- nhmrc : 428206
- PURL : https://purl.org/au-research/grants/nhmrc/428206
