Functional assessment of CD40 in the development of Multiple Sclerosis [ 2014 - 2016 ]

Research Grant

Researchers: Dr Judith Field (Principal investigator) ,  Prof David Booth ,  Prof Helmut Butzkueven ,  Prof Trevor Kilpatrick

Brief description Many of the genes which affect susceptibility to Multiple Sclerosis (MS) have recently been identified. Two of these genes were first discovered in an Australian study published in Nature Genetics in 2009. One of these is CD40, which controls immune cell activation. In this project we aim to establish how the genetic variant identified affects the function of the CD40 gene in MS. CD40 may prove to be a good therapeutic target, with agents available to modulate CD40 available already.

Funding Amount $AUD 521,910.07

Funding Scheme Project Grants

Notes Standard Project Grant