Functional assays of immunity to malaria in pregnant women [ 2011 - 2014 ]

Research Grant

Researchers: Dr Philippe Boeuf (Principal investigator) ,  Prof Lars Hviid ,  Prof Stephen Rogerson

Brief description Pregnant women are highly susceptible to malaria due to the adhesion of infected erythrocytes to the placenta. Antibodies to these infected erythrocytes can block their placental adhesion and/or facilitate their clearance by immune cells, improving pregnancy outcomes. We aim at informing vaccine design by better understanding the placental adhesion mechanisms and identifying targets of protective immunity as well as antibody correlates of protection from placental malaria and its consequences.

Funding Amount $AUD 578,905.78

Funding Scheme Project Grants

Notes Standard Project Grant