A functional assay to classify genetic variants in Lynch syndrome [ 2016 - 2017 ]

Research Grant

Researchers: A/Pr Daniel Park (Principal investigator) ,  Dr Daniel Buchanan

Brief description At least one person in every 1000 is affected by Lynch syndrome, in which faulty DNA repair machinery causes high rates of cancer. People with Lynch syndrome can have their risk of cancer cut substantially with regular screening. However, we often struggle to understand whether people with 'non-standard' DNA sequences in particular genes actually have Lynch syndrome. This project develops a simple test that will tell clinicians whether a given sequence change relates to Lynch syndrome or not.

Funding Amount $AUD 375,714.54

Funding Scheme Project Grants

Notes Standard Project Grant