Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/145710]Researchers: Prof Brendan Crabb (Principal investigator)
Brief description In this project we aim to learn about the function of one of the leading malaria vaccine candidates, merozoite surface protein 1 (MSP-1). Although a promising candidate, little is known about the role of this protein in the invasion by parasites of red blood cells or of the likelihood that the parasites will adapt to avoid vaccines based on MSP-1. To address these issues we propose to use the powerful new technology of parasite transfection, that is the ability to insert DNA into parasites to specifically alter its genetic code. We have pioneered this technology and have developed many of the most effective tools for the process. Insight gained from these studies is likely to influence significantly the design and potential uses of MSP-1 as a vaccine to control malaria.
Funding Amount $AUD 70,285.00
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 145710
- PURL : https://purl.org/au-research/grants/nhmrc/145710
