Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/509336]Researchers: Prof Patrick Humbert (Principal investigator)
Brief description Cell polarity is the property of cells to be spatially oriented in a tissue or organ. We have now shown that the gene Scribble, a key regulator of cell orientation, may keep tumour development in check. In this proposal, we will examine how disruption of Scribble promotes cancer using a combination of tissue culture studies and a newly established mouse model. Understanding how this new pathway can regulate tumour development may provide novel targets for therapeutic intervention in cancer.
Funding Amount $AUD 573,557.21
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 509336
- PURL : https://purl.org/au-research/grants/nhmrc/509336
