Function and molecular mechanism of histidine-rich glycoprotein in necrotic cell and pathogen clearance [ 2015 - 2017 ]

Research Grant

Researchers: Dr Mark Hulett (Principal investigator) ,  A/Pr Marc Kvansakul ,  A/Pr Matthew Perugini

Brief description This research proposal is to investigate the molecular mechanism and function of a blood serum protein, histidine-rich glycoprotein (HRG), in protecting against tissue injury caused by inflammation and infection. HRG has been implicated in controlling important aspects of tissue injury by aiding removal of dead cells and pathogens. Understanding the role of HRG in these disease settings may allow the development of approaches for the treatment of inflammatory, autoimmune and infectious disease.

Funding Amount $AUD 525,957.68

Funding Scheme Project Grants

Notes Standard Project Grant