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Data from: Ribifolin, an orbitide from jatropha ribifolia, and its potential antimalarial activity

RMIT University, Australia
Ewan Blanch (Aggregated by)
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=https://figshare.com/articles/Ribifolin_an_Orbitide_from_i_Jatropha_ribifolia_i_and_Its_Potential_Antimalarial_Activity/2182258&rft.title=Data from: Ribifolin, an orbitide from jatropha ribifolia, and its potential antimalarial activity&rft.identifier=3c9b50e254b0913f44a3945566a7fa2d&rft.publisher=RMIT University, Australia&rft.description=Attached file provides supplementary data for linked article. A new orbitide named ribifolin was isolated and characterized from Jatropha ribifolia using mass spectrometry, NMR spectroscopy, quantitative amino acid analysis, molecular dynamics/simulated annealing, and Raman optical activity measurements and calculations. Ribifolin (1) and its linear form (1a) were synthesized by solid-phase peptide synthesis, followed by evaluation of its antiplasmodial and cytotoxicity activities. Compound 1 was moderately effective (IC50 = 42 μM) against the Plasmodium falciparum strain 3D7. &rft.creator=Ewan Blanch&rft.date=2018&rft.relation=http://dx.doi.org/10.1021/np5007668&rft_rights=All rights reserved&rft_rights=CC BY-NC: Attribution-Noncommercial 3.0 AU http://creativecommons.org/licenses/by-nc/3.0/au&rft_subject=Raman optical activity&rft_subject=Cyclic peptides&rft_subject=Latex&rft_subject=Mahafacyclin&rft_subject=Heptapeptide&rft_subject=Proteins&rft_subject=Structural Chemistry and Spectroscopy&rft_subject=CHEMICAL SCIENCES&rft_subject=PHYSICAL CHEMISTRY (INCL. STRUCTURAL)&rft.type=dataset&rft.language=English Access the data

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Attached file provides supplementary data for linked article. A new orbitide named ribifolin was isolated and characterized from Jatropha ribifolia using mass spectrometry, NMR spectroscopy, quantitative amino acid analysis, molecular dynamics/simulated annealing, and Raman optical activity measurements and calculations. Ribifolin (1) and its linear form (1a) were synthesized by solid-phase peptide synthesis, followed by evaluation of its antiplasmodial and cytotoxicity activities. Compound 1 was moderately effective (IC50 = 42 μM) against the Plasmodium falciparum strain 3D7.

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