Full description
The data that support the findings of this study are available from the corresponding author upon request. Aquatic toxicity testing in environmental monitoring and chemical risk assessment is critical to assess water quality for human use as well as predict impact of pollutants on ecosystems. In recent years, studies have increasingly focused on the relevance of sub-lethal effects of environmental contaminants. Sub-lethal toxicity endpoints such as behavioural responses are highly integrative and have distinct benefits for assessing water quality because they occur rapidly and thus can be used to sense the presence of toxicants. Our work describes a Lab-on-a-Chip system for the automated analysis of freshwater cladoceran Daphnia magna locomotory responses to water-born toxicants. The design combines a Lab-on-a-Chip system for Daphnia sp. culture under perfusion with time-resolved videomicroscopy and software tracking locomotory activity of multiple specimens. The application of the system to analyse the swimming behaviour of water fleas exposed to different concentrations of water-born toxicants demonstrated that Lab-on-a-Chip devices can become important research tools for behavioural ecotoxicology and water quality biomonitoring. Subjects
Aquatic toxicity |
Automated analysis |
Behavioural ecotoxicology |
Environmental Science and Management |
Environmental Sciences |
Ecosystems |
Environmental Impact Assessment |
Environmental contaminants |
Lab-on-a-Chip |
Risk assessment |
Sub-lethal toxicity endpoints |
Water quality |
Water quality biomonitoring |
Water-born toxicants |
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Identifiers
- Local : a38818ec6635c0a906784fdb6d7beabd
