grant

Focimatrix regulation of sex steroid hormones in the ovary [ 2008 - 2012 ]

Also known as: Ovarian hormone regulation by extracellular matrix

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/519367]

Researchers: Dr Helen Irving-Rodgers (Principal investigator)

Brief description Sex steroid hormones (e.g. oestrogen and testosterone), are important to male and female health. In the ovarian follicle I identified a novel form of extracellular matrix (focimatrix) which develops in the ovary before the synthetic enzymes needed for sex steroids are present. Using evidence from other tissues, I developed ideas on how this matrix regulates the enzymes for hormone synthesis. I will examine a mechanism by which focimatrix could directly affect steroid hormone production.

Funding Amount $AUD 291,309.62

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF

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Identifiers
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ACN 633 798 857