Flaviviral proteases as viable targets for antiinfective drugs [ 2012 - 2015 ]

Research Grant

Researchers: Prof David Fairlie (Principal investigator) ,  Prof Paul Young

Brief description Viruses hijack the machinery and nutrients of cells they infect in order to reproduce. We will study viral enzymes (proteases) essential for virus replication, use fluorescent probes to learn where the viral enzymes hide and act in infected cells, track the passage of drugs aimed at these enzymes, design drugs to block their actions and stop virus replication, and test antiviral activity against Dengue, West Nile, Japanese Encephalitis and Yellow Fever viruses which infect millions of people.

Funding Amount $AUD 620,716.41

Funding Scheme Project Grants

Notes Standard Project Grant