Extracellular stress defence mechanisms in non-typeable Haemophilus influenzae [ 2019 - ]

Research Grant

Brief description During infection, HOCl (bleach) is produced by host cells in high concentrations, and this project will characterize the currently unknown mechanism of HOCl resistance in the respiratory tract pathogen Haemophilus influenzae. We have already identified three HOCl-responsive protein in H. influenzae, all of which are required for its survival in the host and will now be characterized in detail, paving the way for future translation into clinically relevant practice and novel treatments.

Funding Amount $622,644.00

Funding Scheme Project Grants

Notes Standard Project Grant