Extracellular acidification and its role in disease [ 2012 - 2015 ]

Research Grant

Researchers: Prof Peter Thorn (Principal investigator)

Brief description This proposal focuses on the diseases cystic fibrosis and acute pancreatitis for which there are currently no treatments. In both diseases the affected organs become strongly acidic. Furthermore, these acid changes can be causal in disease progression. However, the source of this acidification is remains unknown. We will identify the routes of acid secretion, the causal role of acidification in disease progression and the effectiveness of treatments aimed at restoring acid-base balance.

Funding Amount $AUD 371,529.10

Funding Scheme Project Grants

Notes Standard Project Grant