Expression and function of fatty acid binding proteins in asthmatic airway epithelium [ 2005 - 2007 ]

Research Grant

Researchers: A/Pr Michael Rolph (Principal investigator)

Brief description Asthma is an inflammatory disease of the lungs that affects over 10% of all Australians. It ranges in severity from mild to life-threatening. Although a number of drugs are currently available for the treatment of asthma, there are many people whose asthma does not respond very well to treatment. We have recently identified a gene called aP2 that is important in the development of asthma. Drugs targeted against this gene may be very useful in the treatment of asthma. In this project, we aim to understand how aP2 is turned on during asthma, and how it contributes to disease development. This information will be essential for designing optimal strategies for drug targeting of the aP2 pathway in asthma.

Funding Amount $AUD 226,500.00

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant