grant

Export of PfEMP1, the major virulence protein of P. falciparum, to the parasite-infected erythrocyte surface [ 2011 - 2013 ]

Also known as: Export of the major virulence protein in malaria

Funded by National Health and Medical Research Council
Managed by The Walter and Eliza Hall Institute of Medical Research
Managed by Walter and Eliza Hall Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1011453]

Researchers: Prof Alan Cowman (Principal investigator) ,  Dr Melanie Rug

Brief description The malaria parasite infects red blood cells in the human host and initiates major remodelling. This involves export of a major virulence protein to the surface of the red blood cell. This research seeks to understand how the parasite exports this protein, a key determinant of disease.

Funding Amount $AUD 588,531.99

Funding Scheme Project Grants

Notes Standard Project Grant

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Related Publications

  • Associated with Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum
    handle : 2440/88606

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Subjects
Medical and Health Sciences | Medical Microbiology | Medical Parasitology | antimalarial | infectious diseases | malaria | malaria control | malaria vaccine | parasitology | trafficking | virulence factors |
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