grant

Exploring Scanning Ultrasound (SUS), a novel method to treat and prevent neurodegenerative disease [ 2018 - 2021 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1145580]

Researchers: Prof Jurgen Gotz (Principal investigator) ,  Dr Rebecca Nisbet

Brief description We developed a novel scanning ultrasound (SUS) protocol that clears toxic protein aggregates and restores memory function in mouse models of Alzheimer's disease (AD), without the need for therapeutic agents. Here we aim to determine whether SUS has preventative potential, whether there are synergistic effects, and whether a therapeutic antibody combined with SUS leads to an enhanced therapeutic outcome. Together this will guide the development of an ultrasound therapy in AD patients.

Funding Amount $AUD 776,427.92

Funding Scheme Project Grants

Notes Standard Project Grant

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