grant

Exploring the role of microRNA and target processing variability in cardiac hypertrophy [ 2012 - 2014 ]

Also known as: Shifting roles of RNA in cardiac disease

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1024852]

Researchers: Prof Thomas Preiss (Principal investigator) ,  Dr Jennifer Clancy The Australian National University (Managed by)

Brief description microRNAs are gene regulators with critical roles in heart disease. How interactions between microRNAs and their messenger RNA targets change during disease is poorly understood. We hypothesise that these interactions are critically affected by altered processing of microRNAs and targets. We will thus characterise and validate such differences in healthy and diseased hearts. This will define gene regulatory changes underpinning heart disease and contribute to the search for better treatment.

Funding Amount $AUD 605,190.35

Funding Scheme Project Grants

Notes Standard Project Grant

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