grant

Exploring the mechanisms of generation of intestinal TH17 responses and the mechanisms of TH17 mediated pathology [ 2010 - 2012 ]

Also known as: Targeting intestinal TH17 inflammation

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/604304]

Researchers: Dr Rajaraman Eri (Principal investigator) ,  Dr Brent Mckenzie Prof Matthew Cook Prof Michael Mcguckin Prof Timothy Florin

Brief description Our research recently described a mouse that shows excellent similarities to human inflammatory bowel diseases. We further show that the disease mediating substances called cytokines are also similar between our mouse and UC. Particularly, a recently described network of cytokines that are the major mediators of disease in our mice and human IBD. This project examines how we can best interfere with the actions of these cytokines to treat and prevent intestinal inflammation.

Funding Amount $AUD 617,531.44

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Identifiers
Viewed: [[ro.stat.viewed]]